Venlafaxine (Effexor) is a prescription drug used to treat major depression, anxiety, social phobia, and panic disorder. This eMedTV page takes a look at the best time to take Lexapro. As this page discusses, if Lexapro causes insomnia, try taking it in the morning; if it causes drowsiness, try taking it before bedtime. This page also provides other dosing tips for Lexapro. This eMedTV page discusses the best time to take Wellbutrin. As this page explains, it is important to take your Wellbutrin doses at the same time each day to maintain an even level in your blood. This page also provides other Wellbutrin dosing tips. I've been taking it for a week now. I work 7am to 5pm. I started taking it at night (9pm) and noticed I was becoming very tired by noon, but sleeping at night better then ever. Effexor is a dual purpose antidepressant released by Wyeth-Ayerst Laboratories and approved by the FDA in October 1997. Effexor boosts serotonin levels in the synapse in similar fashion to other SSRI's. Effexor (venlafaxine) was the first antidepressant in the class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It is available in an extended-release formula to treat depression, and anxiety and panic disorders. Effexor XR (venlafaxine ER) is an extended-release SNRI used to treat depression, anxiety, and panic disorder. It works by increasing the amount of serotonin and norepinephrine available in the brain. Amanda1525, I took Effexor xr in the morning for years as that was how it was prescribed. But, I always felt so tired out and sleepy. Finally, about six months ago I switched it to bedtime and I now I get a good night sleep which I was never got before, because I have insommia, without the feeling of being so dragged out & tired all day long. Effexor women. Animal Data Metformin HCl did not adversely affect development outcomes when administered to effexor pregnant rats and effexor rabbits at doses up to 600 mg/kg/day. You may find that filling a 90-day supply will reduce your total cost for this prescription. As an added bonus, you'll make fewer trips to the pharmacy, saving you time and money.